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New Auto-Refill Option Enhances Safety of R&D/Process
Development Lyophilization
Liquid Nitrogen trap safeguards operators and equipment
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Stone Ridge, NY May 22,2003
Contact: Leslie Mather
845.687.5315

FTS Systems announces the introduction of an auto-refilling liquid nitrogen trap as an accessory for the LyoStar II® R&D freeze-dryer. The new option provides increased process and equipment safety in the lyophilization of formulations utilizing non-aqueous low-temperature solvents.

According to product manager Leslie Mather, “Increasing numbers of applications are utilizing these solvents that do not condense fully on traditional –55°C or even –85°C condensers. This can reduce the longevity of condenser components and vacuum pumps.” Mather adds, “Some solvents, such as ethanol, liquefy in the traditional condenser, and can contact chamber doors and gaskets. This can cause hairline cracks and gasket damage which can mean down-time and higher maintenance costs.”

The Auto-Refilling LN2 trap safeguards the process and the freeze-drying system by providing an additional ultra-low temperature condensing area. Auto-refilling also means that operator handling of the trap and any potentially dangerous contact with the LN2 is minimized. The freeze-drying process becomes more automated as the trap can be switched on line at the start of the freezing cycle. The trap controller monitors the level of LN2 throughout the freeze-drying process to maintain a constant supply. Robust design minimizes evaporation and reduces risk of spillage while maintaining excellent vacuum integrity.

About the LyoStar II R&D Freeze-Dryer: The LyoStar II is an R&D and process development freeze-dryer that provides unmatched process accuracy, reliability and unique ease-of-use features. The LyoStar II features RTD-controlled shelf temperature accuracy of +/- 0.5°C or better and vacuum control within 0.1% of set-point. Its robust 5.5 hp cascade refrigeration system enables shelf pull down from ambient to –40°C in less than 25 minutes, and the ultra-reliable scroll compressors feature just 3 moving parts . LyoStar II’s unique integrated arm-mounted touchscreen controls enable the operator to manage and monitor operations at the unit.

About FTS Systems: For more than 30 years, FTS Systems has been a leading maker of innovative R&D, process development and production freeze-dryers, and other thermal management systems. Based in Stone Ridge, NY, FTS is part of Kinetics Thermal Systems,
a member of the Kinetics Group.